Microbiota ocular y cirugía de cataratas

Uno de los principales riesgos para los pacientes sometidos a cirugía de cataratas es la infección intraocular.

Esto puede provocar problemas graves, incluida la pérdida de la visión. En este contexto, la evaluación de la microbiota ocular puede ser útil para prevenir tales complicaciones.

Un estudio reciente ha demostrado que el pretratamiento con antibióticos puede afectar la composición de la microbiota ocular y su respuesta a la infección postoperatoria.

Por lo tanto, la identificación adecuada de la microbiota ocular puede ayudar a identificar pacientes en riesgo y personalizar el tratamiento antibiótico pre y postoperatorio.


  1. Yao K, Zhuang H, Zhu H, et al. The impact of intraoperative antibiotics on the microbiota of the anterior chamber during phacoemulsification cataract surgery. Am J Ophthalmol. 2019;208:209-215. doi:10.1016/j.ajo.2019.03.021
  2. Wenkel H, Streit F, Kasper M, et al. The bacterial flora in the conjunctival sac of healthy individuals. Graefes Arch Clin Exp Ophthalmol. 2000;238(9):768-774. doi:10.1007/s004170000156
  3. Ngo W, Chuang E, Cox K, et al. Effects of prophylactic and therapeutic moxifloxacin on the ocular flora. Eye (Lond). 2008;22(6):742-750. doi:10.1038/sj.eye.6702705
  4. Kato N, Tamada K, Suzuki T, et al. Reduction of conjunctival bacterial flora in patients with cataract using povidone-iodine before surgery. Am J Ophthalmol. 2006;141(1):38-42. doi:10.1016/j.ajo.2005.08.011
  5. Hori Y, Nakazawa T, Maeda N, et al. Comparison of 0.5% levofloxacin ophthalmic solution and 1.5% gatifloxacin ophthalmic solution for bacterial conjunctivitis. Jpn J Ophthalmol. 2007;51(3):191-196. doi:10.1007/s10384-007-0445-y
  6. Ahmed IIK, Packer M, Porela-Tiihonen S, et al. Evaluation of the safety and efficacy of Moxifloxacin Ophthalmic Solution 0.5% for the prophylaxis of postoperative endophthalmitis. J Cataract Refract Surg. 2007;33(9):1572-1580. doi:10.1016/j.jcrs.2007.05.037
  7. Matsumura T, Shirakawa R, Suto C, et al. Characterization of the ocular surface microbiome in preoperative patients with myopia. Eye Contact Lens. 2019;45(4):229-235. doi:10.1097/ICL.0000000000000546
  8. Vazirani J, Wurity S, Ali MH, et al. Safety and efficacy of topical moxifloxacin 0.5% ophthalmic solution in preventing conjunctival bacterial flora alteration following cataract surgery: results of a randomized, placebo-controlled trial. Clin Ophthalmol. 2016;10:1149-1156. doi:10.2147/OPTH.S108054
  9. Eissa SA, Khalil NM, Abdelhafez MA, et al. Comparison of two different prophylactic antibiotics in cataract surgery. Clin Ophthalmol. 2020;14:149-157. doi:10.2147/OPTH.S236165
  10. Leloğlu N, Kocabaş A, Yenice T, et al. Comparison of the effects of moxifloxacin and gatifloxacin on the bacterial flora of the conjunctiva. J Ocul Pharmacol Ther. 2009;25(2):165-170. doi:10.1089/jop.2008.0113

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Tagged in: Ocular Dysbiosis

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