Ocular microbiota and cataract surgery
One of the main risks for patients undergoing cataract surgery is intraocular infection.
This can lead to serious problems, including loss of vision.
In this context, evaluation of the ocular microbiota may be useful to prevent such complications.
A recent study has shown that pretreatment with antibiotics can affect the composition of the ocular microbiota and its response to postoperative infection.
Therefore, proper identification of the ocular microbiota can help identify patients at risk and personalize pre-and post-operative antibiotic treatment.
- Yao K, Zhuang H, Zhu H, et al. The impact of intraoperative antibiotics on the microbiota of the anterior chamber during phacoemulsification cataract surgery. Am J Ophthalmol. 2019;208:209-215. doi:10.1016/j.ajo.2019.03.021
- Wenkel H, Streit F, Kasper M, et al. The bacterial flora in the conjunctival sac of healthy individuals. Graefes Arch Clin Exp Ophthalmol. 2000;238(9):768-774. doi:10.1007/s004170000156
- Ngo W, Chuang E, Cox K, et al. Effects of prophylactic and therapeutic moxifloxacin on the ocular flora. Eye (Lond). 2008;22(6):742-750. doi:10.1038/sj.eye.6702705
- Kato N, Tamada K, Suzuki T, et al. Reduction of conjunctival bacterial flora in patients with cataract using povidone-iodine before surgery. Am J Ophthalmol. 2006;141(1):38-42. doi:10.1016/j.ajo.2005.08.011
- Hori Y, Nakazawa T, Maeda N, et al. Comparison of 0.5% levofloxacin ophthalmic solution and 1.5% gatifloxacin ophthalmic solution for bacterial conjunctivitis. Jpn J Ophthalmol. 2007;51(3):191-196. doi:10.1007/s10384-007-0445-y
- Ahmed IIK, Packer M, Porela-Tiihonen S, et al. Evaluation of the safety and efficacy of Moxifloxacin Ophthalmic Solution 0.5% for the prophylaxis of postoperative endophthalmitis. J Cataract Refract Surg. 2007;33(9):1572-1580. doi:10.1016/j.jcrs.2007.05.037
- Matsumura T, Shirakawa R, Suto C, et al. Characterization of the ocular surface microbiome in preoperative patients with myopia. Eye Contact Lens. 2019;45(4):229-235. doi:10.1097/ICL.0000000000000546
- Vazirani J, Wurity S, Ali MH, et al. Safety and efficacy of topical moxifloxacin 0.5% ophthalmic solution in preventing conjunctival bacterial flora alteration following cataract surgery: results of a randomized, placebo-controlled trial. Clin Ophthalmol. 2016;10:1149-1156. doi:10.2147/OPTH.S108054
- Eissa SA, Khalil NM, Abdelhafez MA, et al. Comparison of two different prophylactic antibiotics in cataract surgery. Clin Ophthalmol. 2020;14:149-157. doi:10.2147/OPTH.S236165
- Leloğlu N, Kocabaş A, Yenice T, et al. Comparison of the effects of moxifloxacin and gatifloxacin on the bacterial flora of the conjunctiva. J Ocul Pharmacol Ther. 2009;25(2):165-170. doi:10.1089/jop.2008.0113
Tagged in: Ocular Dysbiosis
Ocular microbiome and the healthy eye
The healthy eye microbiome is composed of a variety of microorganisms, including bacteria, viruses, fungi, and protozoa.
Ocular microbiome and contact lenses
The ocular microbiome of the contact lens wearer may be different than that of a person who does not wear contact lenses.
Ocular microbiota and keratitis
Keratitis is an inflammation of the cornea, the transparent part of the eye that covers the iris and pupil.
Ocular microbiome and dry eye
The ocular microbiome plays an important role in regulating ocular inflammation and producing tear film, which is critical to keeping the eye hydrated and preventing dry eye.
Ocular microbiome and Vernal syndrome
Vernal syndrome is a chronic inflammatory pathology of the eye that mainly affects children and young adults.
Ocular microbiome and Stainer syndrome
Stainer syndrome is a rare ophthalmic pathology that occurs when a bacterial, viral or fungal infection spreads from the skin or mucous membranes adjacent to the eye to the conjunctival mucous membrane...
Ocular microbiota and antibiotic therapy
Antibiotic therapy is a commonly used treatment for bacterial eye infections.
Ocular microbiota and probiotic therapy
Probiotic therapy is a therapeutic strategy that involves the use of living or dead microorganisms to improve the health of the host.
Ocular microbiota and diagnosis of systemic diseases
Some systemic diseases, such as diabetes, rheumatoid arthritis and multiple sclerosis, can also occur at the eye level.
Ocular microbiota and blepharitis
Blepharitis is one of the most common diseases of the eye and can be caused by various factors, including an alteration of the ocular microbiota.
Ocular microbiota and personalized medicine
Personalized medicine involves the use of genetic, environmental and lifestyle information to develop personalized diagnosis, prevention and treatment strategies for patients.
Ocular microbiota and immune system
Studies on the ocular microbiota have shown the presence of a wide range of bacterial species, some of which may have a protective role against certain eye diseases.