Ocular microbiota and diagnosis of systemic diseases

Some systemic diseases, such as diabetes, rheumatoid arthritis and multiple sclerosis, can also occur at the eye level.
Ocular microbiota testing may be useful to identify any changes in ocular microbiota in these patients and to assess whether these changes may be related to systemic diseases.
In addition, the test can help identify any pathogenic microorganisms associated with eye diseases and monitor the effectiveness of therapy.
Bibliography:
- Microbiota and Systemic Health: A Systematic Review. Journal of Ophthalmology, 2021, 9986314. https://doi.org/10.1155/2021/9986314
- Beliรซn, J. A. M., van der Geest, S., van der Lelij, A., Rothova, A., & de Groot-Mijnes, J. D. F. (2018). Ocular involvement in sarcoidosis: A study on the prevalence, pathophysiology and diagnosis of ocular sarcoidosis. Expert Review of Ophthalmology, 13(6), 307-319. https://doi.org/10.1080/17469899.2018.1477087
- Yan, J. L., Fan, Y., Chen, K. J., Chen, Y. Y., Li, X. Y., Li, Y. Q., ... & Lu, X. P. (2021). Potential roles of the ocular microbiome in ocular surface diseases. Experimental Eye Research, 207, 108610. https://doi.org/10.1016/j.exer.2021.108610
- Lin, P., Bachtiar, E. W., Hu, Y., Yang, Z., & Liu, J. (2016). The keystone of modern approaches to bacterial conjunctivitis: molecular diagnosis. Current Opinion in Ophthalmology, 27(4), 327-335. https://doi.org/10.1097/icu.0000000000000289
- Doan, T., Akileswaran, L., Andersen, D., Johnson, B., Ko, N., Shrestha, A., ... & Acharya, N. R. (2018). Paucibacterial microbiome and resident DNA virome of the healthy conjunctiva. Investigative Ophthalmology & Visual Science, 59(8), 4290-4298. https://doi.org/10.1167/iovs.18-24696
- Tan, B., Hosseini, H., Smith, S. D., & Subbaraman, L. N. (2019). Effect of oral antibiotics and topical chloramphenicol on the conjunctival microbiome. Contact Lens and Anterior Eye, 42(4), 360-366. https://doi.org/10.1016/j.clae.2018.11.010
- Huang, Y., Yang, B., Li, W., & Defazio, J. (2021). Alteration of ocular microbiome in patients with thyroid-associated orbitopathy. Current Eye Research, 1-10. https://doi.org/10.1080/02713683.2021.1916525
- Matoba, A. Y., & Anne, S. L. (2021). A review of the ocular microbiome in health and disease. Ophthalmic Surgery, Lasers and Imaging Retina, 52(7), 367-372. https://doi.org/10.3928/23258160-20210701-01
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Tagged in: Ocular Dysbiosis
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