Ocular microbiota and immune system

Studies on the ocular microbiota have shown the presence of a wide range of bacterial species, some of which may have a protective role against certain eye diseases.

In particular, the interaction between the ocular microbiota and the host immune system appears to play a key role in regulating the local inflammatory response, through the production of pro - and anti-inflammatory interleukins.

Some research suggests that the ocular microbiota may influence the production of interleukin-17 (IL-17), which plays an important role in innate immunity against certain bacterial infections.

Similarly, some bacterial species of the ocular microbiota appear to be able to modulate the production of interleukin-10 (IL-10), an anti-inflammatory cytokine that plays an important role in preventing excessive immune response that could damage eye tissues.


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